Successful long-term hematological and immunological reconstitution by autologous cord blood transplantation combined with post-transplant immunosuppression in two children with severe aplastic anemia.
autologous umbilical cord blood transplantation
immunosuppression
severe aplastic anemia
Journal
Pediatric transplantation
ISSN: 1399-3046
Titre abrégé: Pediatr Transplant
Pays: Denmark
ID NLM: 9802574
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
31
07
2018
revised:
17
08
2018
accepted:
12
10
2018
pubmed:
9
11
2018
medline:
26
2
2019
entrez:
9
11
2018
Statut:
ppublish
Résumé
aUCBT is a valuable curative option in pediatric patients with refractory idiopathic SAA and no available matched sibling or unrelated donors. Experience in the use of autologous cord blood units in patients with SAA is limited and private for-profit cord blood-banking programs are controversial. We report the successful treatment of two patients with SAA, aged 15 and 24 months, with autologous cord blood combined with immunosuppression. After conditioning with 200 mg/kg cyclophosphamide and ATG, 7.5 mg/kg, 32.2 × 10
Substances chimiques
Immunosuppressive Agents
0
Cyclosporine
83HN0GTJ6D
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13320Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2018 Wiley Periodicals, Inc.