The combinatory effect of Cyt1Aa flexibility and specificity against dipteran larvae improves the toxicity of Bacillus thuringensis kurstaki toxins.
Aedes
/ drug effects
Amino Acid Sequence
Animals
Bacillus thuringiensis
/ metabolism
Bacterial Proteins
/ metabolism
Bacterial Toxins
/ pharmacology
Endotoxins
/ pharmacology
Hemolysin Proteins
/ metabolism
Larva
/ drug effects
Pest Control, Biological
/ methods
Sensitivity and Specificity
Sequence Alignment
Cyt1A98 expression
Cyt1Aa flexibility
Larvicidal activity improvement
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
15 Feb 2019
15 Feb 2019
Historique:
received:
24
09
2018
revised:
31
10
2018
accepted:
31
10
2018
pubmed:
6
11
2018
medline:
11
4
2019
entrez:
5
11
2018
Statut:
ppublish
Résumé
Cyt1A98 is a novel cytolytic protein, from BUPM98 Bacillus thuringiensis strain, characterized by its synergistic activity with B. thuringiensis kurstaki toxins against lepidopteran larvae. In this study, we evidenced that Cyt1A98 improves the toxicity of B. thuringiensis kurstaki toxins against Aedes aegypti larvae. In fact, the strain BNS3pHTcyt1A98 exhibited a larvicidal activity of about 849-fold of that of BNS3pHTBlue against A. aegypti. The molecular and biochemical characterizations, of cyt1A98 gene and its product, were achieved. Cyt1A98 had an LC
Identifiants
pubmed: 30391590
pii: S0141-8130(18)35100-6
doi: 10.1016/j.ijbiomac.2018.10.226
pii:
doi:
Substances chimiques
Bacterial Proteins
0
Bacterial Toxins
0
Endotoxins
0
Hemolysin Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
42-49Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.