Subtyping of IPMN.

Biomarkers, Tumor / analysis Biopsy Humans Immunohistochemistry / instrumentation Mucins / analysis Pancreatic Intraductal Neoplasms / pathology
Gastric Intestinal MUC1 MUC2 MUC5AC MUC6 Oncocytic Pancreatobiliary

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2019
Historique:
entrez: 1 11 2018
pubmed: 1 11 2018
medline: 7 6 2019
Statut: ppublish

Résumé

Intraductal papillary mucinous neoplasms (IPMNs) characteristically consist of mucin-filled dilated ducts lined with neoplastic cells forming papillae with a diverse range of morphologies and varying grades of atypia. Based on morphological characteristics and immunohistochemical reaction against mucin proteins, IPMNs are classified into four distinct subtypes: gastric, intestinal, pancreatobiliary, and oncocytic. In this chapter, histomorphological criteria and techniques of immunohistochemical staining and its evaluation for subtyping IPMNs are described.

Identifiants

DOI: 10.1007/978-1-4939-8879-2_1 PMID: 30378039
pubmed: 30378039
doi: 10.1007/978-1-4939-8879-2_1
doi:

Substances chimiques

Biomarkers, Tumor 0
Mucins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-8

Auteurs

Toru Furukawa (T)

Department of Histopathology, Tohoku University Graduate School of Medicine, Sendai, Japan. toru.furukawa@med.tohoku.ac.jp.

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Classifications MeSH

Recherchemedicale.com › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Subtyping of IPMN.
Recherchemedicale.com › Techniques d'investigation › Techniques cytologiques › Cytodiagnostic › Biopsie › Subtyping of IPMN.
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Subtyping of IPMN.
Recherchemedicale.com › Disciplines des sciences naturelles › Chimie › Biochimie › Immunohistochimie › Subtyping of IPMN.
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Glycoprotéines › Mucoprotéines › Mucines › Subtyping of IPMN.
Recherchemedicale.com › Maladies endocriniennes › Tumeurs des glandes endocrines › Tumeurs du pancréas › Tumeurs intracanalaires pancréatiques › Subtyping of IPMN.