The effect of wound complications following mastectomy with immediate reconstruction on breast cancer recurrence.


Journal

American journal of surgery
ISSN: 1879-1883
Titre abrégé: Am J Surg
Pays: United States
ID NLM: 0370473

Informations de publication

Date de publication:
03 2019
Historique:
received: 24 07 2018
revised: 12 10 2018
accepted: 13 10 2018
pubmed: 24 10 2018
medline: 21 11 2019
entrez: 24 10 2018
Statut: ppublish

Résumé

The aim of this study was to determine whether complications following mastectomy with immediate breast reconstruction (IBR) were associated with breast cancer recurrence. A retrospective review was performed of women diagnosed with stage I-III breast cancer who underwent mastectomy with IBR between 2005 and 2010. Patient demographics, tumor data, surgical wound complications, treatment details and timing were recorded and analyzed. We identified 458 women with a median follow up time of 7.6 years. A total of 22% of patients experienced IBR complications. There was a delay in initiation of adjuvant therapy in patients who had a complication (52 vs 41 days, p < 0.001). There was no significant difference in recurrences between groups with and without complications (p = 0.65). In breast cancer patients who undergo mastectomy with IBR, wound complications delayed initiation of adjuvant systemic therapy, but were not associated with an increased risk of cancer recurrence.

Identifiants

pubmed: 30348443
pii: S0002-9610(18)31027-4
doi: 10.1016/j.amjsurg.2018.10.028
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

514-518

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Stephanie A Valente (SA)

Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, United States. Electronic address: valents3@ccf.org.

Yitian Liu (Y)

Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, United States.

Siddhi Upadhyaya (S)

Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, United States.

Chao Tu (C)

Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, United States.

Debra A Pratt (DA)

Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, United States. Electronic address: deprat@ccf.org.

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Classifications MeSH