Alcohol consumption in adolescence is associated with a lower risk of multiple sclerosis in a Danish cohort.


Journal

Multiple sclerosis (Houndmills, Basingstoke, England)
ISSN: 1477-0970
Titre abrégé: Mult Scler
Pays: England
ID NLM: 9509185

Informations de publication

Date de publication:
10 2019
Historique:
pubmed: 21 8 2018
medline: 1 7 2020
entrez: 21 8 2018
Statut: ppublish

Résumé

Due to the possible existence of a vulnerable period of multiple sclerosis (MS) susceptibility in adolescence and because Danish teenagers have a high alcohol consumption, we investigated the association between alcohol consumption at ages 15-19 and the risk of developing MS. A total of 1717 patients with MS and 4685 healthy blood donors filled in a comprehensive environmental and lifestyle questionnaire. Data were analysed by logistic regression models and adjusted for selected confounders. We found an inverse association between alcohol consumption in adolescence and risk of developing MS in both women ( Alcohol consumption in adolescence was associated with lower risk of developing MS among both sexes.

Sections du résumé

BACKGROUND AND OBJECTIVE
Due to the possible existence of a vulnerable period of multiple sclerosis (MS) susceptibility in adolescence and because Danish teenagers have a high alcohol consumption, we investigated the association between alcohol consumption at ages 15-19 and the risk of developing MS.
METHODS
A total of 1717 patients with MS and 4685 healthy blood donors filled in a comprehensive environmental and lifestyle questionnaire. Data were analysed by logistic regression models and adjusted for selected confounders.
RESULTS
We found an inverse association between alcohol consumption in adolescence and risk of developing MS in both women (
CONCLUSION
Alcohol consumption in adolescence was associated with lower risk of developing MS among both sexes.

Identifiants

pubmed: 30124094
doi: 10.1177/1352458518795418
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1572-1579

Auteurs

Christina Andersen (C)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Helle Bach Søndergaard (HB)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Ditte Bang Oturai (D)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Julie Hejgaard Laursen (JH)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Stefan Gustavsen (S)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Nanna Katrine Larsen (NK)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Melinda Magyari (M)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
The Danish Multiple Sclerosis Registry, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Emilie Just-Østergaard (E)

Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Lise Wegner Thørner (LW)

Department of Clinical Immunology, Centre of Diagnostic Investigation, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Finn Sellebjerg (F)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Henrik Ullum (H)

Department of Clinical Immunology, Centre of Diagnostic Investigation, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Annette Bang Oturai (AB)

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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Classifications MeSH