Does enamel matrix derivative application improve clinical outcomes after semilunar flap surgery? A randomized clinical trial.
Dental enamel proteins
Esthetics
Gingival recession/therapy
Tooth root/surgery, surgical flap
Journal
Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
received:
02
10
2017
accepted:
30
05
2018
pubmed:
28
6
2018
medline:
14
6
2019
entrez:
28
6
2018
Statut:
ppublish
Résumé
To evaluate the treatment of gingival recessions by semilunar coronally positioned flap plus enamel matrix derivative (SCPF + EMD). Thirty patients with class I localized gingival recession were included. They were randomly allocated in two groups: SCPF + EMD and SCPF. Recession height (RH), recession width (RW), width of keratinized tissue (WKT), thickness of keratinized tissue (TKT), probing depth (PD), and clinical attachment level (CAL) were measured at baseline, 6 and 12 months post-surgery. Patient/professional evaluation of esthetics and root sensitivity was performed. After 12 months, mean root coverage was 1.98 ± 0.33 mm for SCPF + EMD (90.86 ± 14.69%) and 1.85 ± 0.41 mm (79.76 ± 17.44%) for SCPF (p > 0.05). The esthetic evaluation by the patient showed preference for SCPF + EMD. According to the professional evaluation (QCE), the use of EMD decreases the appearance of postoperative scar tissue line. There was a significant reduction in root hypersensitivity with no further complaints by the patients. The addition of EMD provides significantly better esthetics to SCPF, according to patient and professional assessments. SCPF + EMD is effective but not superior to SCPF for root coverage, after 12 months. Previous clinical trials showed that the combination of EMD with coronally advanced flaps may enhance the outcome of root coverage. There is a lack of studies testing the combination of EMD with SCPF. The combination SCPF + EMD provides better esthetics when compared to the SCPF and is effective, but not superior, to SCPF for root coverage, after 12 months. NCT02459704.
Identifiants
pubmed: 29948276
doi: 10.1007/s00784-018-2506-y
pii: 10.1007/s00784-018-2506-y
doi:
Substances chimiques
Dental Enamel Proteins
0
enamel matrix proteins
0
Banques de données
ClinicalTrials.gov
['NCT02459704']
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Pagination
879-887Commentaires et corrections
Type : ErratumIn
Références
J Periodontol. 2006 Dec;77(12):2031-9
pubmed: 17209788
J Periodontol. 1985 Dec;56(12):715-20
pubmed: 3866056
J Periodontol. 2000 Nov;71(11):1693-8
pubmed: 11128916
J Clin Periodontol. 2014 Apr;41 Suppl 15:S36-43
pubmed: 24640999
J Periodontol. 2012 Jun;83(6):707-20
pubmed: 22050544
J Periodontol. 2007 Sep;78(9):1695-701
pubmed: 17760538
Orthod Craniofac Res. 2009 Aug;12(3):243-53
pubmed: 19627527
J Clin Periodontol. 2014 Apr;41 Suppl 15:S44-62
pubmed: 24641000
J Dent. 2008 Sep;36(9):659-71
pubmed: 18584934
J Periodontal Res. 2015 Feb;50(1):103-12
pubmed: 24824040
J Periodontol. 2006 Jul;77(7):1274-9
pubmed: 16805693
Gen Dent. 2000 Jan-Feb;48(1):68-71; quiz 72-3
pubmed: 11199557
J Periodontol. 2009 Jul;80(7):1076-82
pubmed: 19563287
J Periodontol. 2009 Jan;80(1):41-7
pubmed: 19228088
J Clin Periodontol. 2014 Jun;41(6):593-603
pubmed: 24708338
J Periodontol. 2006 Jan;77(1):7-14
pubmed: 16579697
Pract Proced Aesthet Dent. 2006 Aug;18(7):449-54; quiz 456
pubmed: 17001835
J Esthet Dent. 1994;6(2):61-4
pubmed: 7993675
J Clin Periodontol. 2008 Sep;35(8 Suppl):136-62
pubmed: 18724847
J Clin Periodontol. 2016 May;43(5):461-8
pubmed: 26847486
J Periodontal Res. 2007 Oct;42(5):474-85
pubmed: 17760826
J Clin Periodontol. 1986 Mar;13(3):182-5
pubmed: 3457805
J Clin Periodontol. 2005 Nov;32(11):1181-7
pubmed: 16212581
J Periodontol. 2006 Feb;77(2):174-81
pubmed: 16460241
J Clin Periodontol. 1997 Sep;24(9 Pt 2):658-68
pubmed: 9310870
Periodontol 2000. 2001;27:97-120
pubmed: 11551302
Clin Adv Periodontics. 2011 Aug;1(2):101-117
pubmed: 32698558
J Periodontal Res. 2015 Apr;50(2):220-30
pubmed: 25039691
J Periodontal Res. 2015 Oct;50(5):555-69
pubmed: 25418917
J Clin Periodontol. 2002;29 Suppl 3:178-94; discussion 195-6
pubmed: 12787218
J Clin Dent. 1994;5 Spec No:87-92
pubmed: 8534380